HBV S Gene Premature Stop Codon in Strains From Middle Eastern Patients
نویسندگان
چکیده
منابع مشابه
hbv s gene premature stop codon in strains from middle eastern patients
conclusions: premature stop codon in the s gene was observed in all countries with evaluable hbv genome sequences. co-existence of detectable hepatitis b surface antigen (hbsag) and s gene premature stop codon was inconsistent with other studies. investigations on yield truncated hbsag are suggested to determine if they can affect elisa hbsag results. background: we have previously reported on ...
متن کاملA global investigation of gene deletion strains that affect premature stop codon bypass in yeast, Saccharomyces cerevisiae.
Protein biosynthesis is an orderly process that requires a balance between rate and accuracy. To produce a functional product, the fidelity of this process has to be maintained from start to finish. In order to systematically identify genes that affect stop codon bypass, three expression plasmids, pUKC817, pUKC818 and pUKC819, were integrated into the yeast non-essential loss-of-function gene a...
متن کاملA hereditary bleeding disorder resulting from a premature stop codon in thrombomodulin (p.Cys537Stop).
In this study, we describe a novel thrombomodulin (TM) mutation (c.1611C>A) that codes for a change from cysteine 537 to a premature stop codon (p.Cys537Stop). Three members of a family with a history of posttraumatic bleeding were identified to be heterozygous for this TM mutation. All coagulation screening tests, coagulation factor assays, and platelet function test results were within normal...
متن کاملPresence of HBV S-gene mutants in immunocompromised patients.
Hepatitis B virus (HBV) is responsible for a serious, potentially fatal disease that affects approximately two billion people worldwide. Although an extended HBV immunization program has run since 1991, representing the most effective preventive measure possible, leading to a dramatic reduction of HBV hepatitis incidence, 4.5 million new HBV infections still occur every year. In 1988 the emerge...
متن کاملMolecular Characterization of HBV Strains Circulating among the Treatment-Naive HIV/HBV Co-Infected Patients of Eastern India
Previously we reported that the exposure to hepatitis B virus (HBV) infection serves as a major threat among the treatment naive HIV infected population of eastern India. Hence, molecular characterization of these strains is of utmost importance in order to identify clinically significant HBV mutations. A total of 85 treatment naive HIV/HBV co-infected participants were included of whom the com...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Clinical Infectious Diseases
سال: 2012
ISSN: 2345-2641
DOI: 10.5812/archcid.14410